Radiofrequency Ablation Versus Endoscopic Submucosal Dissection in Treating Large Early Esophageal Squamous Cell Neoplasia

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Radiofrequency Ablation Versus Endoscopic Submucosal Dissection in Treating Large Early Esophageal Squamous Cell Neoplasia

Radiofrequency ablation (RFA) and endoscopic submucosal dissection (ESD) can potentially be applied for early esophageal squamous cell neoplasia (ESCN); however, no study has directly compared these 2 modalities.We retrospectively enrolled the patients with flat-type "large" (length ≥3 cm extending ≥1/2 of the circumference of esophagus) early ESCNs treated endoscopically. The main outcome meas...

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Radiofrequency ablation for early esophageal squamous cell neoplasia.

Esophageal cancer is the sixth most common cause of cancer death in the world [1]. Over 80% of esophageal cancers occur in developing countries [1], and in these areas, 90% of these cancers are esophageal squamous cell carcinoma (ESCC) [2]. The precursor lesion of ESCC is squamous intraepithelial neoplasia (squamous dysplasia), defined histologically as nuclear atypia (enlargement, pleomorphism...

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A randomised trial of endoscopic submucosal dissection versus endoscopic mucosal resection for early Barrett’s neoplasia

BACKGROUND For endoscopic resection of early GI neoplasia, endoscopic submucosal dissection (ESD) achieves higher rates of complete resection (R0) than endoscopic mucosal resection (EMR). However, ESD is technically more difficult and evidence from randomised trial is missing. OBJECTIVE We compared the efficacy and safety of ESD and EMR in patients with neoplastic Barrett's oesophagus (BO). ...

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Management of esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma

BACKGROUND Endoscopic submucosal dissection (ESD) permits removal of esophageal epithelial neoplasms en bloc, but is associated with esophageal stenosis, particularly when ESD involves the entire circumference of the esophageal lumen. We examined the effectiveness of systemic steroid administration for control of postprocedural esophageal stricture after complete circular ESD. METHODS Seven p...

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Early esophageal carcinoma includes mucosal and submucosal carcinomas with or without the presence of lymph node metastasis. The prognosis is good after surgery (Chen et al., 2013). To those without lymph node metastasis, endoscopic resection, such as EMR and ESD, has been suggested as alternatives to esophagectomy in the treatment of these lesions, the effect can be matched with surgery (Inoue...

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ژورنال

عنوان ژورنال: Medicine

سال: 2015

ISSN: 0025-7974

DOI: 10.1097/md.0000000000002240